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Updated: Jul 9, 2026

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
Published on: August 8, 2022
[Hypertrophic cardiomyopathy: update and nursing assistance]
Samanta Mariano1, Isaac Rosa Marques
1Faculdade de Enfermagem da Universidade de Santo Amaro, São Paulo, SP. samanthapessini@yahoo.com.br
Hypertrophic Cardiomyopathy (HCM) is a genetic heart condition causing left ventricle hypertrophy. This review details its pathophysiology, treatments, and essential nursing care strategies for improved patient outcomes.
Area of Science:
- Cardiology
- Genetics
- Nursing Science
Context:
- Hypertrophic Cardiomyopathy (HCM) is a primary genetic heart disease.
- It leads to left ventricular hypertrophy, potentially causing heart failure (Functional Class III-IV).
- Understanding pathophysiology is crucial for effective management.
Purpose:
- To update knowledge on Hypertrophic Cardiomyopathy (HCM) pathophysiology.
- To correlate therapeutic interventions with nursing assistance.
- To provide a nursing perspective on HCM management.
Summary:
- HCM stems from genetic alterations causing left ventricular hypertrophy.
- Treatments include palliative medications, pacemaker implantation, ventriculoplasty, and heart transplantation.
- Nursing care is framed using standardized Nursing Diagnoses and Interventions.
Impact:
- Highlights the importance of tailored nursing care in HCM management.
- Provides a foundation for evidence-based nursing practice in cardiology.
- Aims to improve patient quality of life through comprehensive care coordination.
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