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Current and future techniques of neuromodulation for bladder dysfunction.

Neil D Sherman1, Cindy L Amundsen

  • 1Division of Urology, Department of Surgery, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, 185 South Orange Avenue, MSB-534, Newark, NJ 07101, USA. shermane@umdnj.edu

Current Urology Reports
|November 29, 2007
PubMed
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Neuromodulation, particularly sacral neuromodulation, offers treatment for bladder dysfunction. Further research into mechanisms and patient selection will enhance its effectiveness and patient satisfaction for urinary issues.

Area of Science:

  • Urology
  • Neuroscience
  • Biomedical Engineering

Background:

  • Neuromodulation is increasingly used for urinary urgency, frequency, urge incontinence, and nonobstructive urinary retention.
  • Advances in micturition physiology and nerve stimulation technology have driven this trend.
  • Sacral neuromodulation via S3 foramen is the most common technique, with ongoing exploration of alternatives.

Purpose of the Study:

  • To review the current state of neuromodulation for bladder dysfunction.
  • To highlight the need for better understanding of its mechanisms and patient response.
  • To discuss the potential for improved efficacy and patient satisfaction.

Main Methods:

  • Review of current neuromodulation technologies for bladder dysfunction.

Related Experiment Videos

  • Discussion of sacral neuromodulation (S3 foramen stimulation).
  • Exploration of ongoing research and challenges in the field.

    • Main Results:

    • Neuromodulation efficacy is limited by uncertain mechanisms of action and unclear patient response prediction.
    • Current patient selection often targets those unresponsive to conservative treatments.
    • The standard testing procedure for neuromodulation is invasive and costly.

    Conclusions:

    • Improved patient selection criteria and a clearer understanding of the mechanism of action are crucial.
    • Enhancing these aspects is expected to increase efficacy and patient satisfaction.
    • Neuromodulation remains a key option for refractory bladder dysfunction.