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Updated: Jul 9, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
Published on: May 30, 2025
Bicycle riding, perineal trauma, and erectile dysfunction: data and solutions
Irwin Goldstein1, Alan L Lurie, John P Lubisich
1San Diego Sexual Medicine, Alvarado Hospital, 6655 Alvarado Road, San Diego, CA 92120, USA. irwingoldstein@sdsm.info
Erectile dysfunction (ED) in aging men often signals systemic vascular issues. In younger men, ED can stem from penile vascular damage, potentially treatable with surgery.
Area of Science:
- Sexual Medicine
- Vascular Biology
- Urology
Background:
- Erectile dysfunction (ED) is increasingly linked to endothelial dysfunction.
- Aging men with risk factors like diabetes and hypertension often present with ED due to systemic vasculopathy.
- Penile vascular damage can cause ED in younger men, even without traditional risk factors.
Purpose of the Study:
- To explore the connection between endothelial dysfunction and erectile dysfunction.
- To highlight the importance of evaluating vasculogenic ED in all age groups.
- To emphasize the role of penile revascularization surgery.
Main Methods:
- Review of clinical and basic science literature on sexual medicine and vascular function.
- Analysis of risk factors associated with ED in aging populations.
- Consideration of trauma-induced vascular changes in younger men.
Main Results:
- Endothelial dysfunction is a common pathway for ED in aging men with metabolic syndrome and cardiovascular risk factors.
- ED in younger men can result from specific penile arterial damage due to trauma.
- Early identification of vasculogenic ED is crucial for appropriate treatment.
Conclusions:
- ED in aging men often indicates underlying systemic vascular disease.
- Younger men experiencing ED may have treatable vasculogenic causes requiring specialized evaluation.
- Penile revascularization surgery offers a potential treatment option for select patients with ED.
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