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Updated: Jul 9, 2026

Identification of Cyclin-dependent Kinase 1 Specific Phosphorylation Sites by an In Vitro Kinase Assay
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Functional flexibility of human cyclin-dependent kinase-2 and its evolutionary conservation

Iveta Bártová1, Jaroslav Koca, Michal Otyepka

  • 1Department of Physical Chemistry, Palacky University, 771 46 Olomouc, Czech Republic.

Protein Science : a Publication of the Protein Society
|November 29, 2007
PubMed
Summary

Cyclin-dependent kinase 2 (CDK2) has rigid and flexible regions. Rigid areas are conserved and crucial for CDK2 function, while flexible regions enable conformational changes for regulation.

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