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Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Assessment of the Abdomen III: Palpation01:23

Assessment of the Abdomen III: Palpation

Palpation is a crucial tactile examination method for assessing abdominal organs and detecting conditions like tenderness, distention, masses, or fluid. It involves both light and deep palpation techniques, each serving specific diagnostic purposes. Light palpation helps identify tenderness and other surface-level indicators, while deep palpation locates and assess abdominal masses and organ boundaries. A skilled professional can gather valuable insights through palpation, including evaluating...
Ostomy Care01:24

Ostomy Care

Introduction
An ostomy is a surgical procedure that creates an artificial opening from the intestines to the outside of the body, allowing for the rerouting of effluent. This opening is known as a stoma. A stoma usually protrudes above the skin surface, appearing pink or red, moist, and round, and it lacks nerve sensations.
There are different types of ostomies, including colostomies, ileostomies, and urostomies:
The Tongue and Taste Buds00:49

The Tongue and Taste Buds

The surface of the tongue is covered with various small bumps called papillae, which either distribute what has been ingested (filiform papillae) or contain the sensory taste (or gustatory) receptor cells (fungiform, circumvallate, and foliate papillae). Embedded within each taste-related papilla are the taste buds—clusters of 30 to 100 gustatory receptor cells.
Oral Cavity01:11

Oral Cavity

The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
Patch Clamp01:18

Patch Clamp

Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...

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Clinical presentation and outcomes of inflammatory bowel disease patients admitted to the intensive care unit.

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Related Experiment Video

Updated: Jul 9, 2026

Arterial Pouch Microsurgical Bifurcation Aneurysm Model in the Rabbit
06:11

Arterial Pouch Microsurgical Bifurcation Aneurysm Model in the Rabbit

Published on: May 14, 2020

Pouch-ouch.

Elana A Maser1, Daniel H Present

  • 1Mount Sinai Medical Center, New York, NY 10029, USA. elana.maser@mssm.edu

Current Opinion in Gastroenterology
|November 29, 2007
PubMed
Summary

Pouchitis, a complication of ileal pouch anal anastomosis surgery, has identified risk factors and diagnostic markers. Treatment for acute pouchitis involves antibiotics, while chronic cases may benefit from specific medications and surveillance for neoplasia is recommended.

Area of Science:

  • Gastroenterology
  • Surgical Outcomes
  • Inflammatory Bowel Disease Management

Background:

  • Ileal pouch anal anastomosis (IPAA) surgery is a common alternative to permanent ileostomy for patients requiring colectomy, particularly those with ulcerative colitis.
  • While IPAA improves quality of life and self-esteem, pouchitis remains its most frequent complication.
  • This review focuses on recent advancements in understanding and managing pouchitis and associated neoplastic surveillance.

Purpose of the Study:

  • To review current research on the pathophysiology, risk factors, diagnosis, and management of pouchitis.
  • To discuss strategies for pouch surveillance for neoplasia in patients who underwent IPAA for ulcerative colitis.

Main Methods:

  • Literature review of recent research on pouchitis and neoplastic surveillance after IPAA.

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A Rat Model of Pouchitis Following Proctocolectomy and Ileal Pouch-Anal Anastomosis Using Dextran Sulfate Sodium
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A Rat Model of Pouchitis Following Proctocolectomy and Ileal Pouch-Anal Anastomosis Using Dextran Sulfate Sodium

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Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors
04:59

Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors

Published on: September 27, 2019

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Arterial Pouch Microsurgical Bifurcation Aneurysm Model in the Rabbit
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A Rat Model of Pouchitis Following Proctocolectomy and Ileal Pouch-Anal Anastomosis Using Dextran Sulfate Sodium
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  • Analysis of diagnostic markers, identified risk factors, and therapeutic options for pouchitis.

    • Main Results:

    • Inflammatory markers like fecal lactoferrin can differentiate pouchitis from irritable pouch syndrome.
    • Identified risk factors for pouchitis include perinuclear antinuclear cytoplasmic antibodies, prior steroid use, dysplasia as indication for colectomy, extraintestinal manifestations, and elevated platelet count.
    • Antibiotics are standard for acute pouchitis; rifaximin, tinidazole, and budesonide show promise for chronic pouchitis. Surveillance for neoplasia is necessary due to its frequency.

    Conclusions:

    • Discussing identified risk factors for pouchitis with patients is crucial.
    • Less invasive diagnostic methods are being explored, and antibiotics remain the primary treatment for pouchitis.
    • Regular surveillance for neoplasia in the pouch is essential for early detection and management.