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Related Concept Videos

Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...

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Updated: Jul 9, 2026

Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

Asthma and food allergy.

Duygu Ozol1, Emin Mete

  • 1Department of Pulmonology, Fatih University Faculty of Medicine, Ankara, Turkey. dozol@hotmail.com

Current Opinion in Pulmonary Medicine
|November 29, 2007
PubMed
Summary

Food allergies are linked to increased asthma risk and severity, particularly in infants. Diagnosis and treatment, including oral immunotherapy, are crucial for managing these conditions and improving quality of life.

Area of Science:

  • Allergy and Immunology
  • Pulmonology
  • Clinical Medicine

Background:

  • Food allergy prevalence has risen significantly, posing clinical and social burdens.
  • Coexisting asthma exacerbates food reactions, increasing morbidity in all age groups.
  • Early-life food allergy is associated with the development of subsequent asthma.

Purpose of the Study:

  • To review the relationship between food allergy and asthma.
  • To highlight diagnostic challenges and emerging therapeutic strategies.
  • To emphasize the impact of food allergy on asthma control and quality of life.

Main Methods:

  • Review of current literature on food allergy and asthma.
  • Analysis of diagnostic criteria, including specific IgE and skin-prick tests.

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Murine Model of Allergen Induced Asthma
08:05

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

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Last Updated: Jul 9, 2026

Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

Murine Model of Allergen Induced Asthma
08:05

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

  • Evaluation of treatment modalities, focusing on oral immunotherapy.

    • Main Results:

    • Food allergy can precede asthma development, especially in infancy.
    • Accurate diagnostic cut-offs for IgE and skin tests are critical.
    • Oral immunotherapy shows promise for IgE-mediated food allergies.
    • Additives and preservatives, not just foods, can trigger asthma.

    Conclusions:

    • Food allergies are classified as IgE-mediated or non-IgE-mediated.
    • Asthma develops in approximately 5% of food allergy patients; food triggers affect 6-8% of children and 2% of adults.
    • Novel diagnostic and therapeutic approaches are under investigation.
    • Food avoidance is essential for asthma control and improved quality of life in food-allergic individuals.