Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Gastroesophageal reflux disease].

T Castillo Rosales1

  • 1Universidad Nacional Mayor de San Marcos, Lima, Perú.

Revista De Gastroenterologia Del Peru : Organo Oficial De La Sociedad De Gastroenterologia Del Peru
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Effects of the drug HSp-2986 on antral motility, pyloric opening and gastric distensibility. Study with the fibrogastrocamera].

G.E.N·1972
Same journal

[Adolescent with severe liver disease and positive autoantibodies: when Wilson's disease presents as autoimmune hepatitis].

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru·2026
Same journal

[Cholestatic jaundice revealing pylephlebitis associated with mesenteric venous thrombosis].

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru·2026
Same journal

[Severe acute pancreatitis secondary to the use of immune checkpoint inhibitors].

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru·2026
Same journal

[Exocrine pancreatic insufficiency and hyperoxaluria: a preventable renal complication from gastroenterology].

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru·2026
Same journal

[Lymphocytic esophagitis as a cause of dysphagia: a case report and brief literature review].

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru·2026
Same journal

Management of early rectal cancer with massive submucosal invasion using endoscopic intermuscular dissection: a case report.

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru·2026
See all related articles

Gastroesophageal reflux disease (GERD) involves impaired antireflux barriers and acid clearance, leading to esophageal damage. Management includes lifestyle changes, acid inhibitors like H2 receptor antagonists or omeprazole, and surgery for severe cases.

Area of Science:

  • Gastroenterology
  • Digestive Diseases

Context:

  • Gastroesophageal reflux is a common condition with potential for esophageal mucosal damage.
  • Etiology is multifactorial, involving antireflux barrier dysfunction, impaired esophageal acid clearance, and reduced mucosal resistance.
  • Exposure to gastric acid, pepsin, bile salts, and pancreatic enzymes contributes to mucosal injury.

Purpose:

  • To outline the pathophysiology, clinical manifestations, diagnostic approaches, and treatment strategies for gastroesophageal reflux disease (GERD).
  • To highlight the role of diagnostic tools such as endoscopy and 24-hour pH monitoring.
  • To discuss medical and surgical treatment options for GERD.

Summary:

  • Typical GERD symptoms include heartburn and regurgitation, but atypical and pulmonary manifestations can also occur.

Related Experiment Videos

  • Diagnostic methods include clinical history, barium swallow, endoscopy, biopsy, and ambulatory pH monitoring.
  • Treatment focuses on reducing reflux, inhibiting acid, and improving esophageal clearance, incorporating lifestyle modifications, pharmacotherapy (H2 receptor antagonists, omeprazole), and surgery.

    • Impact:

    • Provides a comprehensive overview of GERD for clinicians and researchers.
    • Emphasizes the importance of a multi-pronged approach to GERD diagnosis and management.
    • Informs treatment decisions for patients with varying GERD severity and complications.