Related Experiment Video
Updated: Jul 9, 2026

06:23
Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
Discitis and isthmic spondylolisthesis: a case report.
Yossi Smorgick1, Yizhar Floman, Yoram Anekstein
1Department of Orthopedic Surgery, Assaf Harofeh Medical Center, Zerifin, Israel. Noam_Yossi@Yahoo.com
Journal of Pediatric Orthopedics. Part B
|November 29, 2007
Summary
This case report details a rare instance of coexisting spondylolisthesis and disc space infection in a pediatric patient. Nonoperative treatment led to spontaneous fusion and symptom resolution, allowing a return to sports.
Area of Science:
- Pediatric Orthopedics
- Infectious Diseases
- Spinal Surgery
Background:
- Spondylolysis and spondylolisthesis are frequent causes of pediatric low back pain.
- Disc space infection is a less common but severe cause of back pain in adolescents.
- The simultaneous occurrence of both conditions in the same spinal segment is exceptionally rare.
Observation:
- A 13-year-old male presented with severe low back pain.
- Radiological imaging revealed isthmic lumbosacral spondylolisthesis with endplate irregularities and an anterior bridging osteophyte.
- The patient was diagnosed with a disc space infection at the level of the spondylolisthesis.
Findings:
- The patient underwent a 6-week course of intravenous antibiotics, followed by 2 weeks of oral medication.
- At 28-week follow-up, spontaneous radiological fusion at the affected spinal segment was observed.
- Complete symptom relief was achieved, enabling the patient to resume sports activities.
Implications:
- Isthmic spondylolisthesis and disc space infection can coexist in pediatric patients.
- Nonoperative management, including antibiotics, can be effective in treating this combined condition.
- Successful treatment can lead to spontaneous spinal fusion and full recovery, allowing return to physical activities.
Related Concept Videos
Herniated Intervertebral Disc l: Introduction
Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Degenerative Disc Disease I: Introduction
Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
Degenerative Disc Disease ll: Pathophysiology
The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
