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IgG4-positive pulmonary disease
Hideo Kobayashi1, Tadasuke Shimokawaji, Soichiro Kanoh
1Division of Respiratory Medicine, Department of Medicine, National Defense Medical College, Namiki, Tokorozawa, Japan. kobahide@ndmc.ac.jp
Abstract:
We report herein high-resolution computed tomography findings from a patient with IgG4-related pulmonary disease for the first time. The 61-year-old male patient complained of low-grade fever, dry mouth, and night sweats. He was diagnosed as having autoimmune pancreatitis, Sjögren syndrome, and elevated serum IgG4. High-resolution computed tomography of the lungs showed dense alveolar consolidation and air bronchograms in bilateral perihilar regions. IgG4-positive lymphoplasmacytes were detected in pulmonary lesions by immunostaining of biopsy samples. IgG4-related pulmonary disease can be associated with various radiologic findings.
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