[The effect of anabolic steroids on proliferative activity of thymocytes]

Testosterone, methandrostenolone during ten-day injections to mice 50 mg/kg decrease mass, quality of DNA and 3H thymidine in Thymus. In vitro these drugs loss 3H-thymidine incorporation at 10(-5) M. Ecdysthene do not influence proliferative activity of thymocytes in vitro and thymolytyc effect in vivo. The present results indicate, that proliferative process may have a functional significance in thymolytycal effects of anabolic steroids.