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Published on: February 2, 2024
Malignant pancreatic carcinoid tumour.
A L Zarina1, A Hamidah, S Z Zulkifli
1Paediatric Haematology & Oncology Unit, Department of Paediatrics, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Cheras 56000, Kuala Lumpur, Malaysia. zarinaal@mail.hukm.ukm.my
Singapore Medical Journal
|November 29, 2007
Summary
Pancreatic carcinoid tumors are rare in children. A 12-year-old girl with a functioning tumor causing hypertensive crisis responded well to chemotherapy and octreotide treatment.
Area of Science:
- Pediatric Oncology
- Endocrinology
Background:
- Pancreatic carcinoid tumors are rare, especially in children.
- Tumor presentation depends on hormone secretion.
- Surgical resection is primary treatment, but hormone hypersecretion causes morbidity.
Observation:
- A 12-year-old girl presented with a hypertensive crisis.
- The patient had a functioning pancreatic carcinoid tumor.
Findings:
- The patient showed a positive response to a combination of chemotherapy and octreotide.
- Octreotide, a somatostatin analogue, managed symptoms and tumor progression.
Implications:
- Biotherapy, specifically octreotide, is a crucial strategy for managing symptomatic pancreatic carcinoid tumors.
- This case highlights effective treatment for rare pediatric neuroendocrine tumors.
