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Cancer control by phytochemicals
Hoyoku Nishino1, Yoshiko Satomi, Harukuni Tokuda
1Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyou-ku, Kyoto 602-8566, Japan. cha-nishino@nifty.com
Current Pharmaceutical Design
|November 30, 2007
Summary
Cancer chemoprevention using phytochemicals is a promising strategy. This review covers molecular targets and highlights cancer-preventive compounds like carotenoids.
Area of Science:
- Oncology
- Molecular Biology
- Nutritional Science
Background:
- Chemoprevention is a vital cancer control strategy.
- Phytochemicals offer a molecular mechanism-based approach to cancer prevention.
- Understanding molecular targets is key for effective chemoprevention.
Purpose of the Study:
- To review molecular targets for cancer prevention.
- To present examples of cancer-preventive phytochemicals.
- To highlight the potential of phytochemicals in cancer control.
Main Methods:
- Literature review of chemoprevention strategies.
- Overview of molecular targets in cancer development.
- Compilation of data on phytochemicals with cancer-preventive properties.
Main Results:
- Several molecular targets for cancer prevention have been identified.
- Phytochemicals, including carotenoids, demonstrate cancer-preventive potential.
- Mechanism-based chemoprevention by phytochemicals is a feasible strategy.
Conclusions:
- Phytochemicals represent a significant avenue for cancer chemoprevention.
- Targeting specific molecular pathways with phytochemicals can aid cancer control.
- Further research into carotenoids and other phytochemicals is warranted.
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