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Published on: January 16, 2019
Physical activity in infants with Down syndrome receiving a treadmill intervention
Rosa Angulo-Barroso1, Amy R Burghardt, Meghann Lloyd
1Motor Development Laboratory and Center for Motor Behavior and Pediatric Disabilities, Division of Kinesiology, University of Michigan, 401 Washtenaw Avenue, Ann Arbor, MI 48109, USA. rangulo@umich.edu
Insights
Higher intensity treadmill training (TMT) in infants with Down syndrome (DS) significantly increased moderate-to-vigorous physical activity (PA-level) compared to lower intensity training. These benefits persisted post-intervention, suggesting TMT intensity is crucial for improving PA in infants with DS.
Area of Science:
- Pediatric Physical Therapy
- Developmental Pediatrics
- Down Syndrome Research
Background:
- Physical activity is vital for child development and health, yet its assessment in infants, particularly those with Down syndrome (DS), remains challenging.
- Treadmill training (TMT) is a potential intervention to enhance physical activity levels (PA-level) in infants experiencing motor delays.
Purpose of the Study:
- To compare the effectiveness of a higher intensity, individualized TMT protocol (HI) versus a lower intensity, generalized TMT protocol (LG) on PA-level in infants with DS.
- To determine if higher intensity TMT elicits immediate and short-term increases in PA-level in infants with DS.
Main Methods:
- Thirty infants with DS were randomized into either the LG or HI TMT group.
- Activity monitors assessed PA-level (separating sedentary-to-light activity [Lowact] and moderate-to-vigorous activity [Highact]) during intervention and at 1-year follow-up.
- Training ceased upon independent walking (three steps).
Main Results:
- Infants in the HI TMT group exhibited significantly higher levels of Highact compared to the LG group, excluding intervention-related activity.
- The LG group spent more time in Lowact than the HI group.
- The observed differences in PA-level were maintained at the 1-year post-intervention follow-up.
Conclusions:
- Higher intensity TMT is more effective in increasing moderate-to-vigorous physical activity in infants with DS than lower intensity TMT.
- The positive effects of HI TMT on PA-level appear to be sustained long-term.
- Further research is warranted to explore the precise relationship between TMT intensity, PA-level, motor milestone achievement, and health benefits in infants with DS.
Abstract:
Despite the recognized relevance of physical activity in the development and health of children, assessment of physical activity levels (PA-level) in infancy is limited, especially in infants with Down syndrome (DS). Increasing PA-level using a treadmill training (TMT) intervention may benefit infants with motor delays. The purpose of this study was to investigate whether a higher intensity, individualized TMT protocol (HI) would elicit immediate and short-term higher PA-level in infants with DS than a lower intensity, generalized training protocol (LG). Thirty infants with DS were randomly assigned to the LG or the HI group. Training was terminated when the infants could walk three steps independently. Activity monitors were placed on infants' trunks and legs for a 24-h period every other month during the intervention phase, and at set intervals 1-year post-independent walking onset. Data were analyzed to separate sedentary-to-light activity (Lowact) and moderate-to-vigorous activity (Highact). Overall our results demonstrate that infants receiving the HI TMT had higher levels of Highact than infants in the LG group, factoring out the activity produced by the intervention itself. Infants in the LG group spent more time in Lowact than the HI group. In addition, these results seemed to be retained during the post-intervention follow-up. Despite these exciting results, more work is needed to understand the relationship of the intensity of TMT on PA-level in infants with DS, and whether PA-level and TMT are related to motor milestone achievement and/or health benefits.
