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Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice
Published on: September 19, 2016
The immunological principles underlying vaccine-induced protection in the occupational health setting
1Epidemiology and Health Sciences, Stopford Building, Manchester University Medical School, Oxford Road, Manchester, UK. baxter@nhs.net
Abstract:
Abstract Protection against the large numbers of pathogenic microbes to which humans are constantly exposed is effected through external barriers (skin and mucus membranes), innate barriers (cellular components and soluble chemical mediators) and adaptive barriers (B and T lymphocytes). This article reviews the normal mechanisms employed to protect against these pathogenic microbes.
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