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Amnioinfusion in preterm PROM: effects on amnion and cord histology
A Locatelli1, M Andreani, A Ghidini
1Department of Obstetrics and Gynecology, University of Milano-Bicocca, Monza, Italy. anna.locatelli@unimib.it
Objective:
To investigate the effects of transabdominal amnioinfusion (TA) on the histology of amnion (A) and umbilical cord (UC).
Study Design:
From a cohort of 56 singleton pregnancies with premature rupture of membranes (PROM) at
Result:
Women who consented to TA underwent a median of three procedures had a gestational age at PROM of 18.7 weeks and at delivery of 26.1 weeks, with a latency of 50 days. Compared with subjects who declined the procedure, TA had a beneficial effect on clinical variables, mediated primarily by a longer latency. TA was not associated with identifiable effects on the histologic features of A or UC.
Conclusion:
A and UC histology is not significantly affected by exposure to saline solution even for prolonged periods of time.
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