Lipogranuloma of the cervix in a postmenopausal patient with a uterine prolapse

Lipogranuloma is a rare inflammatory reactive process related to exogenous or endogenous lipids with an admission to the dermis and subcutis. It is described most frequently in the penis and scrotum of young adults. Lipogranuloma of the female genitalia is a rather uncommon condition. The lesion is histopathologically characterized by fat vacuoles with foreign body type giant cells and scattered lymphocytes.

We described an incidental lipogranuloma of the cervix in a 60-year-old woman who presented with total uterine prolapse.

Although lipogranuloma mostly occurs in young male patients, especially in the genital tract, clinicians should be aware of this entity in the cervix of a postmenopausal woman with uterine prolapse, which may challenge the differential clinical diagnosis.