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Related Concept Videos

Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
Chronic Obstructive Pulmonary Disease-I: Introduction01:20

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
Chronic Obstructive Pulmonary Disease I: Introduction01:23

Chronic Obstructive Pulmonary Disease I: Introduction

Chronic obstructive pulmonary disease is a common, preventable, and treatable respiratory disorder characterized by persistent symptoms and progressive airflow limitation. This limitation results from a combination of small-airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), both driven by chronic inflammation from exposure to harmful particles or gases.The disease includes two main pathological entities: emphysema, marked by destruction of alveolar walls and...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...

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Updated: Jul 9, 2026

Machine Learning-Based Cough Tone Classification: Diagnostic Exploration of Chronic Obstructive Pulmonary Disease and Respiratory Tract Infections
06:22

Machine Learning-Based Cough Tone Classification: Diagnostic Exploration of Chronic Obstructive Pulmonary Disease and Respiratory Tract Infections

Published on: September 19, 2025

Cough and its importance in COPD.

Jaclyn Smith1, Ashley Woodcock

  • 1North West Lung Centre, South Manchester University Hospitals Trust, Southmoor Road, Manchester M23 9LT, UK. jackyannsmith@hotmail.com

International Journal of Chronic Obstructive Pulmonary Disease
|December 1, 2007
PubMed
Summary
This summary is machine-generated.

Chronic cough in COPD patients is common and impacts quality of life. Further research is needed to understand cough

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Machine Learning-Based Cough Tone Classification: Diagnostic Exploration of Chronic Obstructive Pulmonary Disease and Respiratory Tract Infections
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Area of Science:

  • Pulmonary Medicine
  • Respiratory Health

Background:

  • Chronic Obstructive Pulmonary Disease (COPD) patients frequently experience breathlessness and cough, which worsen during exacerbations.
  • Current research often focuses on end-stage COPD, neglecting cough's impact across disease stages.
  • Limited data exists on cough frequency, severity, and influencing factors in COPD.

Purpose of the Study:

  • To investigate the frequency, severity, and quality of life impact of cough in COPD patients.
  • To explore factors influencing objective cough counts in COPD.
  • To assess cough reflex sensitivity in COPD and its relation to airflow obstruction.

Main Methods:

  • Review of existing literature on cough in COPD.
  • Analysis of patient-reported outcomes and objective cough monitoring (details not specified in abstract).
  • Comparison of cough reflex sensitivity between COPD patients, asthma subjects, and healthy volunteers.

Main Results:

  • Cough reflex sensitivity is heightened in COPD, similar to asthma, and independent of airflow obstruction.
  • The degree of airflow obstruction does not predict cough reflex sensitivity or objective cough counts.
  • Effective treatments for COPD-related cough have not been identified.

Conclusions:

  • Cough is a significant symptom in COPD, potentially indicating disease progression, especially in smokers.
  • Understanding cough's role in COPD natural history and patient experience is crucial.
  • Development of improved outcome measures and effective treatments for cough in COPD is needed.