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Published on: August 7, 2017

Risk factors of developing asthma in children with recurrent wheezing in the first three years of life

N Cortés Alvarez1, M A Martín Mateos, A M Plaza Martín

  • 1Paediatric Allergy and Clinical Inmunology Section. Sant Joan de Déu Hospital-Clínic Hospital. University of Barcelona. Spain. 33891nca@comb.es

Allergologia Et Immunopathologia
|December 1, 2007
PubMed

Insights

Identifying early asthma risk factors in children with recurrent wheezing is crucial. Atopy is a significant predictor, suggesting early intervention can prevent severe asthma development.

Area of Science:

  • Pediatric Pulmonology
  • Allergy and Immunology

Background:

  • Recurrent wheezing is common in early childhood, making future asthma prediction challenging.
  • Identifying high-risk children early is vital for timely intervention.

Purpose of the Study:

  • To investigate risk factors for developing asthma in children under three with recurrent wheezing.
  • To analyze the association between atopy and asthma development in this cohort.

Main Methods:

  • Prospective study of 60 children under three with recurrent wheezing.
  • Analysis of age, sex, personal/parental history of atopy, clinical features, and treatment response.

Main Results:

  • A majority of patients were boys, with initial wheezing episodes after six months.
  • Personal (63%) and parental (55%) history of atopy were common.
  • Atopic children experienced more exacerbations, poorer outcomes, and increased treatment needs.

Conclusions:

  • Personal and parental history of atopy are key indicators for asthma risk in young children.
  • Early identification of atopic children with recurrent wheezing allows for timely intervention to potentially prevent irreversible airway changes.
Abstract

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