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Updated: Jul 9, 2026

Polarization-Sensitive Two-Photon Microscopy for a Label-Free Amyloid Structural Characterization
Published on: September 8, 2023
Evidence for particle-shape sensitivity in the correlation between polarization states of light scattering
Abstract:
The cross correlation between polarization states of scattered laser speckle as a function of scattering angle is observed for a range of spherical and nonspherical particle suspensions. A variation in the degree of correlation between polarization states is observed, and this information is indicative of the particle shape. A comparison with a theoretical model for small particles is made, suggesting that variations in polarization correlation with angle originate from the nonisotropic polarizability of nonspheres. Experiments are also performed on large spheroids and random-shaped polydispersions, and the results indicate that the measurement method has significant potential for nonsphere detection and characterization.
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