Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neurophysiological methods in C. elegans: an introduction.

William R Schafer1

  • 1Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093-0634, USA.

Wormbook : the Online Review of C. Elegans Biology
|December 1, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An entropic measure of diverse specialization highlights multifunctional neurons in annotated connectomes.

Network neuroscience (Cambridge, Mass.)·2026
Same author

A gene expression atlas of a juvenile nervous system.

bioRxiv : the preprint server for biology·2025
Same author

Neurons, Muscles, and Venom: Identifying Drivers of Cephalopod Predation.

bioRxiv : the preprint server for biology·2025
Same author

Divergence in neuronal signaling pathways despite conserved neuronal identity among Caenorhabditis species.

Current biology : CB·2025
Same author

<i>C. elegans</i> wired and wireless connectome: insights into principles of nervous system structure and function.

Journal of biosciences·2025
Same author

Molecular patterns of evolutionary changes throughout the whole nervous system of multiple nematode species.

bioRxiv : the preprint server for biology·2024
Same journal

Caenorhabditis nomenclature.

WormBook : the online review of C. elegans biology·2018
Same journal

Tubulins in C. elegans.

WormBook : the online review of C. elegans biology·2018
Same journal

History of research on C. elegans and other free-living nematodes as model organisms.

WormBook : the online review of C. elegans biology·2017
Same journal

Development, structure, and maintenance of C. elegans body wall muscle.

WormBook : the online review of C. elegans biology·2016
Same journal

Working with dauer larvae.

WormBook : the online review of C. elegans biology·2016
Same journal

Small GTPases.

WormBook : the online review of C. elegans biology·2016
See all related articles

This chapter details advanced electrophysiology and neuroimaging techniques for studying the Caenorhabditis elegans nervous system. These methods enable in vivo neural activity monitoring and analysis of ion channel function.

Area of Science:

  • Neuroscience
  • Genetics
  • Developmental Biology

Background:

  • The Caenorhabditis elegans nervous system's simplicity makes it a model for behavior research.
  • Physiological methods for in vivo neural monitoring and ion channel studies are emerging.

Purpose of the Study:

  • To present a comprehensive overview of current C. elegans electrophysiology and neuroimaging techniques.
  • To provide protocols and technical reports for researchers.

Main Methods:

  • Calcium imaging in intact C. elegans.
  • In situ electrical recording from neurons and muscle cells.
  • In vitro electrophysiological recording from cultured neurons and oocytes.

Main Results:

Related Experiment Videos

  • Demonstrates the feasibility and application of various electrophysiological and neuroimaging methods in C. elegans.
  • Provides detailed protocols for researchers to replicate and adapt.

    • Conclusions:

    • Electrophysiology and neuroimaging are powerful tools for understanding C. elegans neural function and behavior.
    • This compendium advances research in neurogenetics and behavior using C. elegans.