Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Cell Signaling01:23

Overview of Cell Signaling

Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate with the environment.
Cells respond to many types of information, often through receptor proteins positioned on the membrane. For example, skin cells respond to and transmit touch...
What is Cell Signaling?02:03

What is Cell Signaling?

Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate to respond to the environment.
What is Cell Signaling?02:03

What is Cell Signaling?

Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate to respond to the environment.
Signal Transduction: Overview01:26

Signal Transduction: Overview

Cells respond to many types of information, often through receptor proteins positioned on the membrane. They respond to chemical signals, such as hormones, neurotransmitters, and other signaling molecules, initiating a series of molecular reactions to produce an appropriate response. This is called signal transduction. Cells also coordinate different responses elicited by the same signaling molecule via mediators, allowing molecular cross-talk.
Typically, signal transduction involves three...
Autocrine Signaling01:01

Autocrine Signaling

Autocrine signaling is one of the many signaling mechanisms that function inside multicellular organisms to carry out intercellular communication. In this type of signaling mechanism, the same cell that secretes an extracellular signaling molecule also expresses the receptors to bind and respond to that signaling molecule.
Autocrine Signaling in Macrophages
Under normal physiological conditions, autocrine signaling is essential for maintaining homeostasis. This process is well characterized in...
Autocrine Signaling01:01

Autocrine Signaling

Autocrine signaling is one of the many signaling mechanisms that function inside multicellular organisms to carry out intercellular communication. In this type of signaling mechanism, the same cell that secretes an extracellular signaling molecule also expresses the receptors to bind and respond to that signaling molecule.
Autocrine Signaling in Macrophages
Under normal physiological conditions, autocrine signaling is essential for maintaining homeostasis. This process is well characterized in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Increased Pathogenicity of the Nematophagous Fungus <i>Drechmeria coniospora</i> Following Long-Term Laboratory Culture.

Frontiers in fungal biology·2023
Same author

TENT5 cytoplasmic noncanonical poly(A) polymerases regulate the innate immune response in animals.

Science advances·2022
Same author

Correction to: C. elegans: out on an evolutionary limb.

Immunogenetics·2021
Same author

C. elegans: out on an evolutionary limb.

Immunogenetics·2021
Same author

An integrated view of innate immune mechanisms in C. elegans.

Biochemical Society transactions·2021
Same author

Polyethylene Glycol-mediated Transformation of <i>Drechmeria coniospora</i>.

Bio-protocol·2021

Related Experiment Video

Updated: Jul 9, 2026

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling
09:51

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling

Published on: July 26, 2017

Signaling in the immune response.

Jonathan J Ewbank1

  • 1Centre d'Immunologie de Marseille-Luminy, INSERM/CNRS/Université de la Méditerranée, 13288 Marseille cedex 9, France. ewbank@ciml.univ-mrs.fr

Wormbook : the Online Review of C. Elegans Biology
|December 1, 2007
PubMed
Summary

This study details the innate immune responses in Caenorhabditis elegans (C. elegans) following pathogen infection. It highlights key signaling pathways and molecular mechanisms involved in both immunity and development.

Area of Science:

  • Nematode biology
  • Infectious disease
  • Immunology

Background:

  • C. elegans serves as a model organism for studying innate immunity.
  • Pathogens naturally coexist with C. elegans in its environment.
  • Understanding innate immunity is crucial for host-pathogen interactions.

Purpose of the Study:

  • To summarize current knowledge of C. elegans innate immune responses to infection.
  • To identify and explain the primary signaling pathways involved in C. elegans immunity.
  • To explore the dual role of molecular pathways in both immune and developmental processes.

Main Methods:

  • Review of existing literature on C. elegans immunity.
  • Analysis of identified signaling pathways.
  • Examination of molecular mechanisms shared between immunity and development.

More Related Videos

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
08:32

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production

Published on: March 2, 2014

Real-time Live Imaging of T-cell Signaling Complex Formation
10:31

Real-time Live Imaging of T-cell Signaling Complex Formation

Published on: June 23, 2013

Related Experiment Videos

Last Updated: Jul 9, 2026

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling
09:51

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling

Published on: July 26, 2017

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
08:32

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production

Published on: March 2, 2014

Real-time Live Imaging of T-cell Signaling Complex Formation
10:31

Real-time Live Imaging of T-cell Signaling Complex Formation

Published on: June 23, 2013

Main Results:

  • C. elegans exhibits diverse innate immune responses to various pathogens.
  • Key signaling pathways, such as Toll and Imd pathways, are critical for immune activation.
  • Specific molecular cassettes are involved in both pathogen defense and nematode development.

Conclusions:

  • C. elegans possesses a sophisticated innate immune system.
  • Signaling pathways in C. elegans display functional plasticity, impacting both immunity and development.
  • Further research into these pathways can reveal conserved mechanisms in host defense.