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Updated: Jul 9, 2026

06:27
The Serial Anesthesia Array for the High-Throughput Investigation of Volatile Agents Using Drosophila melanogaster
Published on: February 24, 2023
C. elegans and volatile anesthetics
P G Morgan1, E-B Kayser, M M Sedensky
1Department of Anesthesiology, Case School of Medicine, Cleveland, OH 44106, USA.
Wormbook : the Online Review of C. Elegans Biology
|December 1, 2007
Abstract:
The mechanism of action of volatile anesthetics remains an enigma, despite their worldwide use. The nematode C. elegans has served as an excellent model to unravel this mystery. Genes and gene sets that control the behavior of the animal in volatile anesthetics have been identified, using multiple endpoints to mimic the phenomenon of anesthesia in man. Some of these studies have clear translational implications in more complicated organisms.

