[Time course of relationships of some pathogenetic factors in acute myocardial infarction in rats]

The correlation was examined between the ischemic and necrotic areas, the extent of necrosis, pulmonary tissue edema and duration of early postocclusive arrhythmias in the first 4 hours after coronary occlusion in rat experiments. An hour following coronary ligation, the ischemic area was shown to determine the sizes of a necrotic area, duration of early postocclusive arrhythmias and pulmonary tissue edema. Two hours after myocardial infarction simulation, there was a correlation between the sizes of a ischemic area and pulmonary tissue edema. Four hours after coronary occlusion, the edema of pulmonary tissues was closely related to the sizes of a form necrotic area.