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Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Infection01:20

Infection

When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Determinants of Bacterial Pathogenicity and Virulence01:20

Determinants of Bacterial Pathogenicity and Virulence

Pathogenic bacteria employ a variety of strategies to establish infections, including the secretion of extracellular enzymes that act as potent virulence factors. These enzymes facilitate bacterial colonization of host tissues and help evade immune surveillance. By targeting structural components of host tissues and interfering with immune mechanisms, these enzymes play a pivotal role in disease progression.Extracellular Enzymes Facilitating Tissue Invasion: Several bacterial pathogens secrete...
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Asepsis01:28

Asepsis

The condition of being free from disease-causing living pathogens is asepsis. Aseptic techniques include a set of standard practices to achieve asepsis. An example is the regular environmental cleaning of all parts of the healthcare facility and hand hygiene at home before preparing or eating food. Medical and surgical asepsis in healthcare practice protects patients from harmful pathogens, minimizes the risk of contamination of susceptible sites, and reduces the risk of infection transmission.

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Related Experiment Video

Updated: Jul 9, 2026

In Vivo Mouse Model of Spinal Implant Infection
08:03

In Vivo Mouse Model of Spinal Implant Infection

Published on: June 23, 2020

Surgical site infection: the host factor.

Donald E Fry1, Rosemary V Fry

  • 1Michael Pine and Associates, Chicago, IL, USA.

AORN Journal
|December 7, 2007
PubMed
Summary

Surgical site infections (SSIs) are common complications. Optimizing patient health, including oxygen levels, body temperature, and blood sugar, can significantly reduce infection risk and improve surgical outcomes.

Area of Science:

  • Surgical site infections
  • Infection control
  • Patient physiology

Background:

  • Surgical site infections (SSIs) are a significant postoperative complication, affecting millions of patients annually.
  • While surgical wounds are often contaminated with bacteria, infection development depends on the host's immune response.
  • The patient's physiological state is a critical factor influencing SSI rates.

Purpose of the Study:

  • To highlight the importance of host response in preventing surgical site infections.
  • To identify key physiological factors that can be optimized to reduce SSI risk.
  • To emphasize the role of perioperative nurses in infection control.

Main Methods:

  • Review of factors influencing surgical wound infection.

Related Experiment Videos

Last Updated: Jul 9, 2026

In Vivo Mouse Model of Spinal Implant Infection
08:03

In Vivo Mouse Model of Spinal Implant Infection

Published on: June 23, 2020

  • Identification of patient-centered interventions to mitigate SSI risk.
  • Discussion of the perioperative nurse's role in infection prevention.

    • Main Results:

    • Optimizing patient physiological condition is crucial for preventing SSIs.
    • Key interventions include supplemental oxygen, maintaining core body temperature, and managing blood glucose levels.
    • Proactive infection control by perioperative nurses is vital.

    Conclusions:

    • Enhancing the host's physiological condition is a primary strategy for reducing surgical site infections.
    • Multifaceted approaches focusing on patient optimization and nursing advocacy are essential for SSI prevention.
    • Effective management of patient factors can decrease the incidence of postoperative complications.