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Updated: Jul 9, 2026
10:46
Doppler Optical Coherence Tomography of Retinal Circulation
Published on: September 18, 2012
Quantification of blood flow from rotational angiography
I Waechter1, J Bredno, D C Barratt
1Centre for Medical Image Computing, Department of Medical Physics & Bioengineering, University College London, UK. I.Waechter@cs.ucl.ac.uk
Medical Image Computing and Computer-Assisted Intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
|December 7, 2007
Summary
This study introduces a novel method using rotational angiography to quantify blood flow in cerebrovascular diseases. The technique accurately estimates blood flow waveforms and volumetric rates, aiding in interventions.
Area of Science:
- Medical Imaging
- Biomedical Engineering
- Fluid Dynamics
Background:
- Cerebrovascular diseases require detailed 3D vessel morphology and hemodynamics.
- Rotational angiography is standard for 3D geometry but lacks flow quantification.
Purpose of the Study:
- To develop a method for determining blood flow parameters from rotational angiography.
- To quantify blood flow waveform and mean volumetric flow rate.
Main Methods:
- Utilized a contrast agent dispersion model to analyze spatial-temporal concentration changes.
- Developed a flow map from contrast dynamics and a reliability map to correct for c-arm rotation artifacts.
Main Results:
- Validated the method using computer simulations and phantom experiments.
- Achieved a mean error of 11.0% for mean volumetric flow rate.
- Achieved a mean error of 15.3% for blood flow waveform.
Conclusions:
- The proposed method can provide quantitative blood flow estimates during cerebrovascular interventions.
- This technique enhances the utility of rotational angiography for assessing cerebrovascular hemodynamics.
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