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Birth Control Methods01:22

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Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although vasectomy...
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[Emergency contraception with levonorgestrel].

Fernando D Saraví1

  • 1Departamento de Morfología y Fisiología, Facultad de Ciencias Médicas, Universidad Nacional de Cuyo, y Escuela de Medicina Nuclear, Mendoza, Argentina. fsaravi@fcm.uncu.edu.ar

Medicina
|December 7, 2007
PubMed
Summary

Emergency contraception using levonorgestrel, a synthetic gestagen, prevents about 80% of pregnancies when used as a backup method. It is most effective when taken early after unprotected intercourse.

Area of Science:

  • Reproductive Health
  • Pharmacology

Context:

  • Emergency contraception (EC) is crucial for preventing unintended pregnancies.
  • Levonorgestrel is a widely recommended oral EC medication.
  • Understanding its efficacy and limitations is vital for public health.

Purpose:

  • To review the efficacy, safety, and utilization of levonorgestrel for emergency contraception.
  • To assess its mechanism of action and potential side effects.
  • To evaluate strategies for improving access and use.

Summary:

  • Levonorgestrel, as a single 1.5-mg dose or two 0.75-mg doses, offers moderate efficacy (approx. 80%) in preventing pregnancy post-unprotected intercourse.
  • Its effectiveness is time-sensitive, being higher when administered sooner, up to 5 days post-coitus.

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  • Common side effects include nausea and menstrual irregularities; its role as an ongoing contraceptive is not advised.
  • Impact:

    • Levonorgestrel EC is a valuable backup method but not a substitute for regular contraception.
    • Despite availability, its use remains underutilized, highlighting a need for better awareness and access.
    • Advance provision strategies have not demonstrably improved pregnancy/abortion rates, reinforcing its backup role.