Related Experiment Video
Updated: Jul 9, 2026

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
Published on: November 12, 2015
Diffuse lamellar keratitis after corneal crosslinking in a patient with post-laser in situ keratomileusis corneal
George D Kymionis1, Dimitrios I Bouzoukis, Vasilios F Diakonis
1Institute of Vision and Optics, University of Crete, Medical School, Department of Opthamology, Crete, Greece. kymionis@med.uoc.gr
Abstract:
A 27-year-old man presented with corneal ectasia in his left eye 4 years after myopic laser in situ keratomileusis (LASIK) and was treated with riboflavin-ultraviolet-A (crosslinking). During the first post-treatment days, diffuse lamellar keratitis (DLK) (stage III) developed. The microbiology culture was negative. After intensive treatment with topical corticosteroids, the DLK resolved during the following 2 weeks. Crosslinking for post-LASIK corneal ectasia may induce DLK. Early diagnosis and appropriate treatment with intensive topical corticosteroids is essential to successfully manage this post-crosslinking complication.

