Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Plasmapheresis in dermatology].

N S Potekaev, M I Kurdina, S L Orlov

    Terapevticheskii Arkhiv
    |January 1, 1991
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Increased expression of uPA, uPAR, and PAI-1 in psoriatic skin and in basal cell carcinomas.

    Archives of dermatological research·2017
    Same author

    [The specific features of gout in the elderly].

    Terapevticheskii arkhiv·2014
    Same author

    [Lipoid necrobiosis in the practical work of a therapist and dermatologist].

    Klinicheskaia meditsina·2013
    Same author

    [Cystatin C level is independently related to risk of unfavorable outcome after acute coronary syndrome in individuals with normal or moderately reduced renal function].

    Kardiologiia·2011
    Same author

    [Interaction of the neurohumoral and immune mechanisms of progression of myocardial damage].

    Terapevticheskii arkhiv·2010
    Same author

    [Role of surgeon in early diagnosis of cancer of the skin].

    Khirurgiia·2005
    Same journal

    [History of the Moscow Scientific Society of Cardiology].

    Terapevticheskii arkhiv·2026
    Same journal

    [Antiphospholipid syndrome: ophthalmologic manifestations. A review].

    Terapevticheskii arkhiv·2026
    Same journal

    [Uric acid and mitochondrial dysfunction: a review].

    Terapevticheskii arkhiv·2026
    Same journal

    [Rheumatoid nodule in the myocardium as part of the chain in a clinical detective. Case report].

    Terapevticheskii arkhiv·2026
    Same journal

    [Immunoglobulin G4-related retroperitoneal fibrosis: clinical, laboratory, imaging, and histopathological features in a Russian single-center cohort].

    Terapevticheskii arkhiv·2026
    Same journal

    [Cutaneous manifestations of systemic lupus erythematosus and coexisting dermatologic conditions].

    Terapevticheskii arkhiv·2026
    See all related articles

    Plasmapheresis (PA) is a safe and effective treatment for dermatoses, with 96% efficacy. This therapy normalized hemostasis and improved immune function in patients.

    Area of Science:

    • Dermatology
    • Immunology
    • Hematology

    Background:

    • Dermatoses can involve complex systemic complications, including disseminated intravascular coagulation (DIC) and immune dysregulation.
    • Hemostasis and microcirculation are often impaired in patients with severe dermatological conditions.

    Purpose of the Study:

    • To evaluate the efficacy and safety of plasmapheresis (PA) in patients with various dermatoses.
    • To assess the impact of PA on hemostasis, microcirculation, and immune parameters in these patients.

    Main Methods:

    • Observation of 105 patients with different dermatoses undergoing plasmapheresis (PA) treatment.
    • Monitoring of hemostatic parameters, microcirculation, and markers of humoral and cellular immunity.
    • Assessment of treatment tolerance and overall efficacy.

    Related Experiment Videos

    Main Results:

    • Plasmapheresis (PA) demonstrated high efficacy (96%) and was well-tolerated by most patients.
    • PA successfully eliminated disseminated intravascular coagulation (DIC) in the majority of patients.
    • Significant improvements were observed in hemostasis, microcirculation, and immune function, including decreased CIC and complement activity, with increased phagocytic index, indicating macrophagal activation.

    Conclusions:

    • Plasmapheresis (PA) is a highly effective and safe therapeutic option for patients with dermatoses, particularly those with DIC.
    • PA exerts a beneficial immunocorrective effect, normalizing immune parameters and activating the macrophagal system.
    • The study supports the use of PA for managing complex dermatological conditions involving hematological and immunological disturbances.