Related Experiment Video
Updated: Jul 9, 2026

07:41
Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats
Published on: October 23, 2020
Detection of glaucoma-like optic discs in a diabetes teleretinal program
Louis R Pasquale1, Baharak Asefzadeh, Robert W Dunphy
1Ocular Telehealth Center, VA Boston Healthcare System-Jamaica Plain Campus, Jamaica Plain, Massachusetts 02130, USA. Louis.Pasquale@va.gov
Summary
A diabetes teleretinal imaging program showed high specificity in identifying glaucoma-suspicious optic discs. However, improvements are needed to increase its sensitivity for early glaucoma detection in diabetic patients.
Area of Science:
- Ophthalmology
- Diabetology
- Medical Imaging
Background:
- Glaucoma is an insidious eye disease with severe vision loss, often linked to diabetes mellitus (DM).
- Assessing optic disc changes is crucial for glaucoma diagnosis.
Purpose of the Study:
- To evaluate the sensitivity and specificity of a diabetes teleretinal program in detecting glaucoma-suspicious optic discs.
- To identify potential modifications for enhancing glaucoma detection within diabetes care programs.
Main Methods:
- A nonmydriatic digital retinal imaging (NMDRI) program was used for 1,644 outpatients with DM.
- Retrospective review of electronic medical records for 175 glaucoma suspects and 175 controls.
- Ophthalmic data from comprehensive eye exams were used to confirm glaucoma-suspicious optic discs.
Main Results:
- 59% (103/175) of glaucoma suspects exhibited glaucoma-suspicious optic discs.
- Only 4% (7/175) of the control group showed suspicious optic discs.
- The program demonstrated high specificity (96%) in identifying glaucoma suspects.
Conclusions:
- The diabetes teleretinal imaging program has high specificity but requires modifications to improve sensitivity for glaucoma detection.
- Enhancing the program can aid in the early identification of glaucoma in diabetic individuals.
Related Concept Videos
Diabetic Retinopathy
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
