Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A computer-assisted image processing method for determining relative cardiac function in the chick embryo.

H J Bruyere1, B Xu, T L James

  • 1University of Wyoming, Laramie 82071.

Teratology
|December 11, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Combination neratinib (HKI-272) and paclitaxel therapy in patients with HER2-positive metastatic breast cancer.

British journal of cancer·2013
Same author

Biallelic DICER1 mutations occur in Wilms tumours.

The Journal of pathology·2013
Same author

ACP5, a direct transcriptional target of FoxM1, promotes tumor metastasis and indicates poor prognosis in hepatocellular carcinoma.

Oncogene·2013
Same author

Ischemic postconditioning protects against focal cerebral ischemia by inhibiting brain inflammation while attenuating peripheral lymphopenia in mice.

Neuroscience·2013
Same author

Fast-track surgery improves postoperative recovery in patients undergoing partial hepatectomy for primary liver cancer: A prospective randomized controlled trial.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2013
Same author

Snacking may improve physical function among older Americans.

The journal of nutrition, health & aging·2013
Same journal

Statement of the Public Affairs Committee of the Teratology Society on the fetal alcohol syndrome.

Teratology·2002
Same journal

Quantification and localization of expression of the retinoic acid receptor-beta and -gamma mRNA isoforms during neurulation in mouse embryos with or without spina bifida.

Teratology·2002
Same journal

Timing of prenatal care initiation and risk of congenital malformations.

Teratology·2002
Same journal

A new rapid radiological procedure for routine teratological use in bone ossification assessment: a supplement for staining methods.

Teratology·2002
Same journal

Dose and litter allocations in the design of teratological studies for detecting hormesis.

Teratology·2002
Same journal

Effect of sera from women with systemic lupus erythematosus or antiphospholipid syndrome and recurrent abortions on human placental explants in culture.

Teratology·2002
See all related articles

This study developed a noninvasive computer-assisted method for quantifying chick embryo cardiac function. The new technique significantly improved precision and reduced processing time compared to manual methods.

Area of Science:

  • Cardiovascular Research
  • Developmental Biology
  • Biomedical Imaging

Background:

  • Assessing cardiac function in embryonic models is crucial for understanding heart development and disease.
  • Existing methods for quantifying cardiac parameters in chick embryos can be time-consuming and lack precision.

Purpose of the Study:

  • To develop and validate noninvasive, computer-assisted methods for determining relative cardiac function parameters in embryonic chick hearts.
  • To compare the precision and efficiency of novel image processing techniques against established manual methods.

Main Methods:

  • Utilized in ovo videography of embryonic chick hearts, followed by digitization and computer-aided image enhancement.
  • Employed region-growing and edge-detection algorithms for quantifying intraventricular blood volume.

Related Experiment Videos

  • Calculated ventricular volumes using prolate spheroid equations based on longitudinal and transverse axis measurements.

    • Main Results:

    • Developed three distinct computer-assisted methods for cardiac volume quantitation.
    • Achieved a mean intraobserver coefficient of variation of 7.4% across all methods.
    • Computer processing reduced the coefficient of variation by 56.5% compared to manual methods, with no significant difference between the three developed methods.

    Conclusions:

    • Computer-assisted image processing offers a precise and efficient noninvasive method for assessing embryonic chick cardiac function.
    • This approach significantly enhances reproducibility and reduces the labor involved in cardiac parameter quantitation.
    • The developed methods provide a valuable tool for research in developmental cardiology and related fields.