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Choosing the appropriate breast cancer therapy for today's breast cancer patient
1Disease Specific Oncology Research and Development, Memorial Cancer Institute, Hollywood, FL 33021, USA. cfrankel@mhs.net
Objectives:
To identify which patients might be the best candidates to receive combination targeted therapies for the treatment of metastatic breast cancer.
Data Sources:
Published research articles, abstracts, and clinical experience.
Conclusion:
Factors including tumor size, age, HER2 positivity, and hormone receptor content help determine the optimal approach toward the treatment of breast cancer in the individual patient. Further research will clarify the role of targeted agents in the adjuvant setting, along with the hope of a cure.
Implications For Nursing Practice:
The oncology nurse must be aware of current and emerging therapies - whether they be intravenously or orally administered - and the proper methods to help characterize patients who might likely benefit from these agents.
Insights
Identifying the best candidates for combination targeted therapies in metastatic breast cancer involves considering tumor size, age, HER2 status, and hormone receptor content. This helps tailor treatment for individual patients.
Area of Science:
- Oncology
- Medical Therapeutics
Background:
- Metastatic breast cancer treatment requires personalized approaches.
- Combination targeted therapies offer new treatment avenues.
Purpose of the Study:
- To identify patient characteristics that predict response to combination targeted therapies for metastatic breast cancer.
Main Methods:
- Review of published research articles.
- Analysis of abstracts and clinical experience.
Main Results:
- Tumor size, patient age, HER2 positivity, and hormone receptor status are key factors.
- These factors influence the selection of optimal treatment strategies.
Conclusions:
- Individualized treatment selection is crucial for metastatic breast cancer.
- Further research is needed to define the role of targeted agents in the adjuvant setting.
- Oncology nurses must be knowledgeable about emerging targeted therapies and patient selection criteria.
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