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Published on: March 28, 2025
Case of pediatric acquired chronic hepatocerebral degeneration
Spiridon Papapetropoulos1, Andreas Tzakis, Cenk Sengun
1Division of Movement Disorders, Department of Neurology, Miller School of Medicine, University of Miami, Miami, Florida 33136, USA. spapapetropoulos@med.miami.edu
Abstract:
Acquired chronic hepatocerebral degeneration is a central nervous system disorder secondary to several conditions related to hepatic dysfunction. Clinical features of acquired chronic hepatocerebral degeneration include a hyperkinetic extrapyramidal syndrome, neuropsychiatric symptoms, or both. We present for the first time a pediatric case of acquired chronic hepatocerebral degeneration secondary to endstage biliary disease. The pediatric phenotype of acquired chronic hepatocerebral degeneration is presented, and the differential diagnosis in regard to Wilson's disease and management alternatives are discussed.
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