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Effect of gold nanoparticles on spermatozoa: the first world report
Viroj Wiwanitkit1, Amornpun Sereemaspun, Rojrit Rojanathanes
1Department of Clinical Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. wviroj@yahoo.com
Objective:
To evaluate the spermatotoxicity of gold nanoparticles.
Design:
Experimental study.
Setting:
A university in Thailand.
Patient(S):
Single-donor fresh semen sample.
Intervention(S):
A mixture of gold nanoparticle solution and semen was prepared and further analyzed.
Main Outcome Measure(S):
Spermatozoa appearance.
Result(S):
After mixing the semen with a gold nanoparticle solution, 25% of sperm were not motile. Penetration of gold nanoparticle into the sperm heads and tails was observed.
Conclusion(S):
Spermatotoxicity of the gold nanoparticle can be detected.
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