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[Synthesis of ST-1435 derivatives as contraceptive for lactating women]
1Research Center for Drugs of Family Planning, China Pharmaceutical University, Nanjing.
Yao Xue Xue Bao = Acta Pharmaceutica Sinica
|January 1, 1991
Abstract:
Four new ST-1435 derivatives 4-7 were synthesized. Both 4 and 5 are mixture of Z- and E-isomers. 4 was separated into Z- and E-isomers by spinning TLC. Their binding ability to progesterone receptor was examined and found to be less than ST-1435.