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InParanoid 6: eukaryotic ortholog clusters with inparalogs

Ann-Charlotte Berglund1, Erik Sjölund, Gabriel Ostlund

  • 1Linnaeus Centre for Bioinformatics, Uppsala University, BMC Box 598, 75124, Uppsala, Sweden.

Nucleic Acids Research
|December 7, 2007
PubMed

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Gene families consist of groups of genes proposed to have originated from a common ancestor. Typically these arise through events in which a gene or genes are mistakenly duplicated during cell division. Unlike their parent genes (which are subject to selection pressure to maintain function), these gene copies do not need to preserve their sequences and may evolve at a relatively faster rate.
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Gene Families01:57

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One of the distinguishing features of eukaryotic cells is that they contain membrane-bound organelles, such as the nucleus and mitochondria, that carry out specialized functions. Since biological membranes are only selectively permeable to solutes, they help create a compartment with controlled conditions inside an organelle. These microenvironments are tailored to the organelle's specific functions and help isolate them from the surrounding cytosol.
For example, lysosomes in the animal cells...
Eukaryotic Compartmentalization01:46

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