Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

KEGGanim: pathway animations for high-throughput data.

Priit Adler1, Jüri Reimand, Jürgen Jänes

  • 1Estonian Biocentre, Riia 23b, Estonia.

Bioinformatics (Oxford, England)
|December 7, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multi-platform reassessment of human mitochondrial DNA methylation reveals signals consistent with technical artifacts.

bioRxiv : the preprint server for biology·2026
Same author

Extracting and Classifying Drug Discontinuations From Estonian Electronic Health Records: Development and Validation Study.

Journal of medical Internet research·2026
Same author

Venous and arterial thromboembolic events after COVID-19 during the Omicron period in three European countries.

Scientific reports·2026
Same author

Therapy-associated mutagenesis at CTCF binding sites is shaped by chromatin context and DNA repair capacity.

bioRxiv : the preprint server for biology·2026
Same author

Experimental assessment of AI-based interactome mapping.

Nature communications·2026
Same author

Extracellular vesicles from aged individuals trigger mitochondrial dysfunction in haematopoietic progenitor cells.

Haematologica·2026
Same journal

3DICE: Interpretable 3D Cross-Modal Learning for Drug-Target Interaction Prediction and Large-Scale Drug Discovery.

Bioinformatics (Oxford, England)·2026
Same journal

KASSPer: Kinase Active Site Structure Prediction using Protein and Ligand Language Models and Its Application to Virtual Screening.

Bioinformatics (Oxford, England)·2026
Same journal

IDR searcher: a search engine solution for public image resources.

Bioinformatics (Oxford, England)·2026
Same journal

KCFtools: Rapid alignment-free method for introgression screening and GWAS using k-mer profiles.

Bioinformatics (Oxford, England)·2026
Same journal

Meta2DB: Curated shotgun metagenomic feature sets and metadata for health state prediction.

Bioinformatics (Oxford, England)·2026
Same journal

conMItion: an R package adjusting confounding factors for associations in multi-omics.

Bioinformatics (Oxford, England)·2026
See all related articles

KEGGanim visualizes high-throughput experimental data on biological pathways, highlighting dynamic gene changes. This tool aids systems biology research by integrating experimental results with pathway knowledge for 14 organisms.

Area of Science:

  • Bioinformatics
  • Systems Biology
  • Genomics

Background:

  • High-throughput methods like microarrays generate vast genome-wide data.
  • Emerging fields like proteomics and interactomics add further data dimensions.
  • Systems biology necessitates integrating diverse experimental data with pathway knowledge.

Purpose of the Study:

  • To develop a web-based tool for visualizing experimental data within biological pathways.
  • To enable researchers to link high-throughput data with existing pathway information.

Main Methods:

  • KEGGanim accepts public or user-uploaded high-throughput data.
  • Visualizes data on KEGG pathways, coloring members by experimental measurements.
  • Animates pathway members across experimental conditions for dynamic analysis.

Related Experiment Videos

Main Results:

  • KEGGanim generates dynamic pathway visualizations, highlighting key genes and modules.
  • Supports data for 14 organisms with extensive public microarray data.
  • Accepts common gene/protein identifiers and microarray probesets.

Conclusions:

  • KEGGanim provides an accessible platform for exploring dynamic biological pathways.
  • Facilitates the interpretation of complex experimental datasets in a systems biology context.