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Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
Published on: January 29, 2018
Determinants of skeletal age deviation in a cross-sectional study
Sandi Powell1, Deqiong Ma, Graeme Jones
1Menzies Research Institute, Private Bag 23, Hobart, Tasmania 7000, Australia.
The Journal of Clinical Endocrinology and Metabolism
|December 7, 2007
Summary
Skeletal age deviation (SAD) in children is linked to body composition, strength, diet, smoking, and corticosteroid use. These factors may influence bone maturity and fracture risk, warranting further investigation into genetic and perinatal influences.
Area of Science:
- Pediatric Endocrinology
- Bone Biology
- Growth and Development
Background:
- Skeletal age deviation (SAD) correlates with bone mass and fracture risk in pediatric populations.
- Understanding the determinants of SAD is crucial for assessing bone health and potential fracture risk in children.
Purpose of the Study:
- To identify factors associated with skeletal age deviation (SAD) in a pediatric cohort.
- To explore the relationship between lifestyle, environmental factors, and bone maturity in children.
Main Methods:
- Cross-sectional study of 640 children aged 7-17 years.
- Assessment of body composition, diet, strength, physical activity, and medication use.
- Skeletal age determination using the Tanner-Whitehouse-2 method.
Main Results:
- Higher height, weight, and Tanner stage were observed in subjects with SAD above the 75th percentile.
- Positive associations found between SAD and lean mass, fat mass, grip strength, and milk consumption.
- Negative associations identified between SAD and ever smoking and inhaled corticosteroid use.
Conclusions:
- Body composition, strength, diet, smoking history, and inhaled corticosteroid use may influence skeletal maturity in children.
- These factors represent potential determinants of SAD and subsequent fracture risk.
- Further research is needed to explore genetic, perinatal factors, and the impact of SAD on peak bone mass.
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