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Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction
Published on: September 14, 2018
Asymmetric synthesis of cyclopropyl-fused 2'-C-methylcarbanucleosides as potential anti-HCV agents
Lak Shin Jeong1, Jeong A Lee, Hea Ok Kim
1College of Pharmacy, Ewha Womans University, Seoul, Korea. lakjeong@ewha.ac.kr
Nucleosides, Nucleotides & Nucleic Acids
|December 7, 2007
Abstract:
Novel 2'-C-methyl-cyclopropyl-fused carbocyclic nucleosides as potential anti-HCV agents were stereoselectively synthesized, utilizing regioselective cleavage of the isopropylidene group and cyclic sulfate chemistry as key steps.
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