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Pyoderma gangrenosum with large circumferential perianal skin loss in a child
1Department of Paediatric Surgery, University Hospital of Wales, Cardiff.
Insights
Pyoderma gangrenosum is a rare skin condition causing deep ulcers. It can sometimes be the first sign of other serious diseases, especially in children.
Area of Science:
- Dermatology
- Internal Medicine
Background:
- Pyoderma gangrenosum is an uncommon ulcerative skin disorder.
- It presents with characteristic deep ulcers and a violaceous, overhanging edge.
- While often idiopathic, it can be associated with systemic conditions.
Abstract:
Pyoderma gangrenosum is an uncommon skin disorder characterised by deep ulcers surrounded by a violaceous over-hanging edge. Although in many instances there is no clear association with any underlying disease, pyoderma gangrenosum has been described in ulcerative colitis, Crohn's disease, polyarthritis, diabetes mellitus and myeloma. Pyoderma gangrenosum may also be seen as a rare manifestation of myeloproliferative disease including leukaemia. In children, as in our case, it may be the presenting feature.