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Updated: Jul 9, 2026

Ex vivo Mimicry of Normal and Abnormal Human Hematopoiesis
Published on: April 10, 2012
Extramedullary hematopoiesis within endothelial papillary hyperplasia (Masson's pseudoangiosarcoma) of the tongue
Carlos Santonja1, Jesús de Sus, Manuel Moragón
1Department of Pathology, Fundación Jiménez Díaz, Madrid. csantonja@fjd.es
Abstract:
We report the unique association of Masson's pseudoangiosarcoma (endothelial papillary hyperplasia) and extramedullary hematopoiesis. The lesion was present as a violaceous nodule on the side of the tongue of a 78-year-old man with history of multiple myeloma and long-standing mild anemia. This association between a peculiar form of thrombus organization and extramedullary hematopoiesis has been reported previously only once, in an infant with a cranial hematoma, and raises interesting pathogenetic questions.
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