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14-3-3 proteins recognize a histone code at histone H3 and are required for transcriptional activation

Stefan Winter1, Elisabeth Simboeck, Wolfgang Fischle

  • 1Max F Perutz Laboratories, Vienna Biocenter, Medical University of Vienna, Vienna, Austria.

The EMBO Journal
|December 7, 2007
PubMed

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The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
Acetylation
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