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Ethanol-induced depletion of cerebellar guanosine 3',5' -cyclic monophosphate
Science (New York, N.Y.)
|July 2, 1976
Abstract:
Single doses of ethanol a severe depletion (95 percent) of cerebellar guanosine 3',5' -cyclic monophosphate (cyclic GMP) within 1 hour after administration. The degree of this depletion is dose-dependent and is a function of the amount of ethanol in the blood. Interactions between ethanol and cyclic GMP may account for some of the intoxicating properties of ethanol.