Related Experiment Video
Updated: Jul 9, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
Published on: May 10, 2024
Eosinophilic esophagitis: association with allergic disorders
1Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 2000, Cincinnati, OH 45229, USA. amal.assa'ad@cchmc.org <amal.assa'ad@cchmc.org>
Abstract:
Atopy has been linked to eosinophilic gastrointestinal disorders because of the role eosinophils play in atopic disorders. It has also been found that these disorders coexist. The goal of this article is to take a step back, and considering only eosinophilic esophagitis, attempt to determine from the available body of clinical and research literature: (1) Is the coexistence of these disorders attributable to a preconceived bias? If so, what is the source of the bias and how can it be removed? (2) Is there a cause and effect relationship? If so, can this relationship be harnessed for diagnostic and therapeutic modalities?
Related Concept Videos
Asthma I: Introduction
Esophageal Achalasia
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Gastroesophageal Reflux Disease
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...

