Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Analyzing effects of vaccines.

A Svensson1

  • 1Stockholm University, Sweden.

Mathematical Biosciences
|December 1, 1991
PubMed
Summary

This study models how varying vaccine protection impacts infection spread. It analyzes vaccine efficacy estimators and links clinical trial results to real-world vaccination program effectiveness.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Suicidal ideation in patients with skin conditions: A multicentre European study.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026
Same author

A cross-sectional study on gender differences in body dysmorphic concerns in patients with skin conditions in relation to sociodemographic, clinical and psychological variables.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024
Same author

Quality of life measurement in urticaria: Position statement of the European Academy of Dermatology and Venereology Task Forces on Quality of Life and Patient-Oriented Outcomes and Urticaria and Angioedema.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024
Same author

Prevalence of prurigo nodularis in Sweden.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024
Same author

Quality of life measurement in teledermatology. Position statement of the European Academy of Dermatology and Venereology Task Forces on Quality of Life and Patient Oriented Outcomes and Teledermatology.

Journal of the European Academy of Dermatology and Venereology : JEADV·2023
Same author

Quality of life measurement in rosacea. Position statement of the European Academy of Dermatology and Venereology Task Forces on Quality of Life and Patient Oriented Outcomes and Acne, Rosacea and Hidradenitis Suppurativa.

Journal of the European Academy of Dermatology and Venereology : JEADV·2023

Area of Science:

  • Epidemiology
  • Biostatistics
  • Mathematical Modeling

Background:

  • Infectious disease spread is influenced by individual susceptibility variations.
  • Vaccine effectiveness can differ among individuals due to varying protective effects.

Purpose of the Study:

  • To model the impact of heterogeneous vaccine effects on infectious disease dynamics.
  • To evaluate different vaccine efficacy estimators using clinical trial data.
  • To explore the relationship between vaccine efficacy and vaccination program effectiveness.

Main Methods:

  • A simple stochastic model was developed to simulate disease transmission.
  • The model incorporated individual variations in susceptibility and vaccine protection.
  • Statistical methods were used to analyze vaccine efficacy estimators.

Main Results:

  • The stochastic model demonstrated diverse effects of vaccination on infection spread based on individual variability.
  • Analysis of vaccine efficacy estimators highlighted their behavior in clinical trial settings.
  • A relationship was established between measured vaccine efficacy and overall program effectiveness.

Conclusions:

  • Individual variability in susceptibility and vaccine response significantly influences disease dynamics.
  • Accurate estimation of vaccine efficacy is crucial for predicting vaccination program success.
  • Understanding these factors is essential for optimizing public health vaccination strategies.

Related Experiment Videos