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Updated: Jul 9, 2026
In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Diagnostic accuracy of computed tomography-guided percutaneous biopsy of renal masses
Joerg Schmidbauer1, Mesut Remzi, Mazda Memarsadeghi
1Department of Urology, Medical University of Vienna, Vienna, Austria. joerg.schmidbauer@meduniwien.ac.at
Objective:
Modern imaging modalities increase the detection of small (
Methods:
Under computed tomography (CT)-fluoroscopic guidance 78 patients with solid renal tumors prospectively underwent 18-gauge core biopsy. In addition, using the same sheath, fine-needle aspiration was taken in 44 patients and analyzed cytologically. The renal masses were subsequently removed surgically and evaluated histologically.
Results:
Mean patient age was 63+/-13.5 yr; mean tumor size was 4+/-1.8 cm. The sensitivity of core biopsy and fine-needle aspiration for the detection of renal cell carcinoma (RCC) was 93.5% and 90.6%, respectively; Fuhrman grade was correctly predicted in 76% and 28% and the correct histologic subtype was identified 91% and 86%, respectively. Cytology from fine-needle aspiration revealed a sensitivity in detecting malignant and benign lesions of 100% and 75%, respectively. Two of the renal tumors diagnosed as oncocytomas on core biopsy were hybrid tumors with scattered areas of oncocytomas and chromophobe RCC. Complications of CT-guided biopsy included one marginal pneumothorax, which resolved under conservative management, and four small perirenal hematomas detected at follow-up ultrasonography not requiring further therapy.
Conclusion:
CT-guided percutaneous preoperative renal tumor biopsy had a high diagnostic accuracy, particularly in predicting malignancy.
