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A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

Published on: January 19, 2024

Ambulatory dysfunction due to unrecognized pernicious anemia.

Robert W Malizia¹, Brigitte M Baumann, Michael E Chansky

¹University of Medicine and Dentistry of New Jersey - Robert Wood Johnson Medical School, Camden, New Jersey 08103, USA.

The Journal of Emergency Medicine

|December 7, 2007

Summary

Pernicious anemia, a condition affecting cobalamin absorption, can cause severe neurological issues. This case highlights its occurrence in younger individuals, urging broader awareness among emergency physicians.

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Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication

Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication

Published on: December 11, 2013

Area of Science:

Hematology
Neurology
Internal Medicine

Background:

Pernicious anemia (PA) is an autoimmune condition leading to vitamin B12 deficiency.
It typically affects elderly Caucasians but is increasingly recognized in diverse demographics.
Reduced cobalamin absorption causes significant hematologic and neurologic impairments.

Observation:

A case of a young Black woman presenting with progressive lower extremity paresthesias, weakness, and ataxia is described.
These symptoms mimicked other neurological disorders, delaying the diagnosis of PA.
This presentation underscores the need to consider PA in younger patients with unexplained ambulatory dysfunction.

Findings:

The case illustrates that PA is not limited to older white populations.
Early diagnosis and management are crucial to prevent irreversible neurologic damage.
Changing demographics of PA necessitate updated clinical suspicion and diagnostic approaches.

Implications:

Emergency physicians should consider PA in younger patients presenting with neurologic symptoms, particularly ambulatory dysfunction.
Awareness of PA's evolving demographic profile is essential for timely diagnosis and treatment.
For women of reproductive age, undiagnosed PA poses risks for fetal and infant health.