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Quantitative PCR-based Assay to Measure Sonic Hedgehog Signaling in Cellular Model of Ciliogenesis
Published on: January 31, 2025
The primary cilia, a 'Rab-id' transit system for hedgehog signaling
1Stanford University, School of Medicine, Stanford, CA 94305, USA. oro@stanford.edu
Current Opinion in Cell Biology
|December 7, 2007
Abstract:
Intense focus has been centered around how the primary cilia transduces the hedgehog (Hh) signal from smoothened (Smo) to the Gli transcription factors. New data indicate that ligand and signaling lipids help regulate small GTPase-dependent accumulation and activity of signaling components.
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