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Orienteering as a Tool for Cognitive Research: An Implementation Guide
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Lost your orientation? Find your way with PtdIns(3,4,5)P3!

Yannick Gachet1, Sylvie Tournier

  • 1LBCMCP-CNRS UMR5088, Institut d'Exploration Fonctionelle des Génomes (IFR109), University of Toulouse, 118 route de Narbonne, 31062 Toulouse, France.

Developmental Cell
|December 7, 2007
PubMed
Summary

Phosphatidylinositol-3,4,5-triphosphate (PtdIns(3,4,5)P3) regulates spindle orientation in metaphase cells. This occurs via the dynein-dynactin motor complex interacting with the actin cytoskeleton at the cell cortex.

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