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Updated: Jul 9, 2026

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model
Published on: September 4, 2017
[Radiation-induced cavernoma of the central nervous system]
A Melot1, A Laquerrière, S Hanzen
1Service de neurochirurgie, CHU de Rouen, 1, rue de Germont, 76031 Rouen cedex, France.
Abstract:
Central nervous system radiation-induced cavernoma (RIC) is a rare entity. We report one case with a review of the literature. This case illustrates the following features: mean age of 11.7 years at time of radiation and mean latency period of nine years for these RIC, which are often numerous (38%), and located in the field of the craniospinal radiation therapy. This nosological entity belongs to the spectrum of radiation-induced lesions, and requires a long-term MRI follow up in patients who underwent cranial radiation therapy.
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