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Updated: Jul 9, 2026
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Endonasal transsphenoidal pituitary surgery: is tumor volume a key factor in determining outcome?
Amit Kumar Jain1, Ashok Kumar Gupta, Ashis Pathak
1Department of Otolaryngology & Head & Neck surgery, Post-Graduate Institute of Medical Education and Research, Chandigarh, India.
Purpose:
This study was conducted to evaluate the role of tumor volume in excision of pituitary adenomas.
Materials And Methods:
A total of 20 patients with pituitary adenoma underwent surgical excision of the tumor by endonasal transsphenoidal approach.
Results:
A preoperative tumor volume of more than 5 mL is associated with a 90.90% probability of residual tumor (P < .05, statistically significant).
Conclusion:
Tumor volume as a predicting factor for the surgical outcome is an evolving concept. Other factors determining the efficacy of tumor removal are parasellar and suprasellar extension.
